PirquetThe term allergy was introduced in 1906 by Clemens von Pirquet. Clemens published in German In the Munchen Med Wehnscher 1906;3 . 24 July. He said that a new generalized term was needed which does not prejudice anything but expresses a change in condition which an animal experiences after contact with any organic poison.Referring to serums and people’s reaction to them he stated “For this general concept of a changed reactivity I propose the term Allergy.” At the time Allos implied a deviation from the original state. Pirquet went on to state “The vaccinated, the tuberculous, the individual injected with serum becomes allergic towards the corresponding foreign substance. A foreign substance, which by one or more application stimulates the organism to change in reaction is an Allergen.”